Dr Byers, supplements and increased cancer risk – Same turgid old stuff.

It seems every five years or so, someone is appointed to jump up and warn us all about Vitamin Supplements and their dangers.

This time Dr Byers got the short straw.

The problem is that we’ve heard it all before, the same research, the same generalisations – and we know the answer.

Out comes the same one-off research study (following an indicative study) on beta-carotene and smoking. Then there is research on vitamin E which has little benefit and may even do harm.

Neither supplement would I touch anyway. Both mass market supplements in the main are deficient, synthetic copies of the real thing. In nature beta-carotene is available in cis- and trans- forms, but only one is used in the common supplement. Vitamin E is worse. Most studies involve synthetic alpha-tocopherol, just one of the eight variants found in nature. In my book it should not even be called vitamin E (it’s fraud).

Synthetic vitamins, for me, carry the same basic risks as synthetic drugs. Natural vitamin E is easy to come by. Put out a bowl of nuts and seeds – a handful of sunflower and pumpkin seeds will give you the four tocotrienol vitamin Es – shown to be much better than tocopherol in fighting cancer anyway.

Folate supplementation is, quite possibly, a threat to all these highly profitable cholesterol-lowering statin drugs, which are under soooo much pressure at the moment from leading heart specialists. They have been linked to a range of secondary illnesses from diabetes to eye sight problems; and research is now questioning whether they do lower death rates from heart attacks and strokes.

Folate, again, is a vitamin you should get from your diet – eat your greens!!!! If you are short you are in trouble. If you have a healthy microbiome (gut bacteria) and eat properly you will be fine; too much you might be in trouble. It has an RDA in ‘micrograms’ for that reason.

But what I love is the way the ‘research’ extrapolates a study on synthetic beta-carotene and smoking to warn the listeners on supplements in general. It would be like me saying that since one drug, Vioxx, killed 48,000 Americans and is now banned, people should be careful when using any drugs because their benefits are questionable and there is clear evidence of significant risks.

Mass market vitamin supplements have limited benefits, although Centrum produced a study a couple of years back showing their multivitamin reduced cancer risk by 7 per cent – this would extrapolate to 22,000 less people with cancer in the UK alone next year. In 2003, the French produced the Su Vi Max study which had followed 17,000 people on selenium and zinc, vitamins E and C and beta-carotene – that showed 31% fewer male cancers (but little change for women); and 37% less deaths overall from cancer over the study period.

I am much more interested in bioactive natural compounds such as vitamin D, curcumin, fish oils, sulforaphanes, CLA, MCP and another 60 with Epigenetic benefits. Now they are interesting. Even Dr Young S. Kim of the NCI in her research on foods that could stop cancer stem cells re-growing, said these could be taken as quality supplements.

Ok. It’s diary time. Which doctor, or preferably professor wants to author this same study on the risks of supplements in 2020?

I’ll have this Junk Science article ready to re-run then too.

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I was asked recently what I thought of ‘alternative medicine’. I replied as I have consistently done for a number of years, ‘There is no such thing as alternative medicine. A treatment either works or it doesn’t’.

If you talk to cancer patients and ask them what they want a treatment to do, it is simply to cure them.
Here I side with Dr. Henry Friedman of the Preston Robert Tisch Cancer Center at Duke University Medical Center, Carolina. He said, on the front page of the website, ‘I believe cancer can be cured; it may be in remission but it can be in remission permanently’. Brave words from a man who treats people with gliomas, which are often described as ‘terminal’.

So his aim is to get a patient into remission and, ideally, even cure them.

Talk to patients. Their aim is to be cured. It’s as simple as that. ‘Manage your cancer with drugs for the rest of your life, madam?’ ‘No thanks, I’d rather be cured.’

This fits with the way things are going for cancer patients too. In a 2012 report, the American Cancer Society concluded that since 2006 there had been an explosion in research into complementary therapies and that there was ‘overwhelming evidence’ that certain of them like diet and exercise could increase survival and even prevent a cancer returning.

Sounds like a result to me. And obviously to patients at large.

Which leads me to the fact that there is a humungous problem with cancer drugs. They don’t cure cancer. In 2012 it was proven beyond any reasonable doubt, that at the heart of all cancers lay cancer stem cells. An ‘inconvenient truth’ is that while drugs can cause a decrease in tumour size of 50, 60 or even 70%, as of today there is not one single drug known to man that kills off the cancer stem cells at the heart of the tumour.

But despite this, 54 per cent of people do beat cancer (or at least survive 5 years – which, I agree, is not really the same).

Cue Dr. Young S. Kim of the National Cancer Institute in America who concluded from her research in 2012, that people who employed a poor diet saw their cancers return. While people who employed a good diet – including foods that were high in sulphoraphanes, curcumin, piperine, EGCG, choline, genistein, vitamin A and E, and a couple of others – could prevent the cancer returning. She even went so far as to say that these bioactive compounds could be obtained via quality supplements.

The fact is, that very few patients nowadays rely on their oncologist’s medicines to cure a cancer. They may use them, but they employ a range of their own treatments from fasting, juice diets, colourful Mediterranean diets, yoga, IVC, weight control, even (perish the thought) localized hyperthermia, HIFU and the dreaded apricot kernels. Several women I know have used a herbal poultice called Black Salve. Oncologists treating the ladies both said the same thing.: Having confirmed that the ‘thing’ in the jar was indeed a tumour, they said they had never seen anything like it. But it was beyond their training and they could comment no more.

Of course not all these treatments have been through ‘The rigours of a clinical trial’. Actually, ‘rigourous trial’ when it comes to drugs is a bit of an oxymoron. Even the FDA has just concluded that almost 40% of drug clinical trials were sloppy and inaccurate. Worse, Peter Grotzsche, the head of the highly respected Nordic Cochrane Centre, has a book called ‘Deadly Medicines and Organised Crime: How Big Pharma has Corrupted Healthcare’. The title says it all. And it is the British Medical Association’s 2014 book of the year!!

Radiotherapy and surgery have hardly a clinical trial between them. Surgery, even biopsies, have been linked to increased metastatic activity. Cutting out a colorectal cancer is certainly no guarantee that the cancer won’t return in your lungs or liver.

Brachytherapy, used for prostate cancer is now used in some parts of America for up to 60% of breast cancers, meriting huge protests. Why? Errr, there are no clinical trials to support it. The new sexy Cyberknife will cause less damage – who says? Show me the proof. Does it prevent a cancer returning?

Meanwhile Hospitals feed the cancer with ice cream, sweet desserts and milky, sugary tea. The drink and snack food dispensers all offer chocolate bars, and cans of fizzy soft drinks full of High Fructose Corn Syrup. Leading cancer charities say there is no harm in feeding cancer patients cows’ dairy and sugar. They are out of their tiny minds. 2014 research showed sugar CAUSED cancer. 2013 research showed people with the highest blood sugar levels survived least.

And so it goes on.

A subplot over the last few years included research from Johns Hopkins that showed chemo drugs actually caused a cancer to return – and stronger; German research that showed Taxol caused metastases 6 months after treatment was finished and Scientists from Harvard Medical School and Massachusetts Amherst showed in research published in January 2015 that some chemotherapy drugs actually caused cancer stem cells to re-grow. Another ‘inconvenient truth’?

So, there are treatments that have the power to prevent a cancer returning. And there are others that don’t. Some may even make matters worse.

The ones that do keep cancers at bay – diet, exercise, quality supplements and a few others, are thus treatments that work. The others – chemo, radio and surgery are but unproven alternatives supported by dodgy research, vested interest, mafia-like unions, some paid skeptics and often simple fraud.

Patients are right to think of self-empowerment. Offering chemical potions that simply don’t give them what they want – preventing a cancer from returning – that’s just unproven alternative medicine.

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What’s in your Vitamin Supplement??

People simply do not realize the rubbish that can be in cheaper vitamin supplements. And by ‘people’, I mean not just the sick, but doctors, researchers and even the scientists who prepare reports praising or condemning them.

Synthetic, deficient and dangerous?

The cheaper versions are often simply synthetic, and deficient versions of the real thing, like Thai copies of Gucci handbags. Should you be surprised when the handle drops off?

But this is your health you are messing with. And matters can get worse when you realise what ‘fillers’ and even toxic ingredients can be incorporated in the tablet.

Unfortunately, most research studies simply talk about ‘vitamin E improving your immune system’ (positive) or ‘vitamin E doing more harm than good’ (negative) without any sensible or responsible comment on the vitamin quality used.

Vitamin E is a classic example of confusion – even the mighty Memorial Sloan-Kettering Medical School gets its commentary wrong on its website!

Vitamin E is available in nature in 8 related forms – 4 tocopherols and 4 tocotrienols. These cousins appear in foods from grains to greens. Memorial Sloan-Kettering refers to all the foods in nature you can find vitamin E within. However, Memorial Sloan-Kettering then refers to vitamin E as alpha-tocopherol, which it is not. Alpha-tocopherol is but one constituent. It certainly is NOT present in all those foods mentioned.

The same applies to UK high street vitamin E, which, thanks largely to EU ‘health’ restrictions is this same constituent form – alpha tocopherol – and, worse, invariably synthetic and made by the petrochemical industry. In a review of a number of research studies by the Nordic Cochrane Institute it was concluded that the ‘vitamin E’ was of little benefit and arguably did more harm than good. A similar issue is found with beta-carotene, which in nature is available in cis- and trans- forms, but in cheap varieties is just one synthetic copy.

To put this in context, experts are agreed that natural vitamin E is effective against ageing, cancer, oxidative damage, diabetes, eye problems and more. Conversely, synthetic petrol-derived vitamin E is an endocrine disrupter!

Unwanted additives

Next there are the ‘innocent additives’. Typically these may include cows’ dairy products, sugar (like maltodextrin), gluten, corn starch, soy products, hydrogenated vegetable oil and yeast.

Then there are warnings on bottles about contra-indications, some of which are relevant while others are little more than scaremongering clap-trap. Inconsistency rules. Sadly, the same doctors who advise patients not to take vitamin supplements whilst taking drugs routinely forget to mention that many drugs have contra-indications with grapefruit and its juice, or with dried meats and eggs.

Fillers and ‘excipients’

The American International Pharmaceutical Council has stated that, ‘Excipients are substances other than the pharmacologically active ingredients, which are included in the manufacturing process or are contained in a finished product. In many products, excipients make up the bulk of the total dosage form’ (Czap, AL, The Townsend Letter For Doctors and Patients, July 1999, Vol.192; pg.117-119).

And it should be noted that such fillers and additives in supplements can ‘cause allergic reactions, impede absorption, and have undesirable physiological effects’. Often manufacturers call such ‘fillers’ by words like ‘glaze’ or ‘natural vegetable coatings’.

Typical compounds include:

1. Magnesium stearate – used as a flow agent to keep manufacturing equipment working smoothly. Made from cottonseed oil. (Concerns have been raised about GMOs, pesticides, T-cell damage and inhibition of drug absorption, but all seem overclaims)

2. BHT (butyl hydroxyl-toluene) – laboratory made chemical, added to various foods and supplements, to prevent rancidity and oxidation. Supplements of it go with claims that it can treat lipid-coated viral disease. But Berkeley Wellness newsletter expresses concerns over safety – the Center for Science in the Public Interest lists BHT in its “caution” column. It may be harmful in high doses.

3. Boric acid – known to have anti-fungal and anti-yeast activities, it has been used as an antiseptic, insecticide and even a flame retardant. It is also connected to DNA damage.

4. Cupric sulphate – Green Med Info is concerned it can contribute to heavy metal toxicity. Can be used as a herbicide, fungicide and pesticide.

5. Sawdust – although you won’t find it on the label some tablets have been shown to contain sawdust.

6. Talcum powder – the same is true for talcum powder, which may have even been dyed.

7. Sodium benzoate – Used as a preservative to stop the presence of moulds and bacteria. Has a known effect against mitochondria.

You get what you pay for

While, there is ample evidence that the levels of the above are small and that they have no negative effects at those concentrations, the question is, ‘Why take cheap supplements containing them?’

In 2012 at The National Cancer Institute, Dr Young Kim produced a study on controlling stem-cell cancer tumours and their re-growth. In that study, Kim identified certain food compounds that could prevent a cancer re-growing, and went on to say, ‘All of the bioactive compounds could be found in quality supplements’.

So what is a quality supplement? The point is that many supplements simply do not fit the bill. Take common vitamin C. Research covered in Cancer Watch at the charity CANCERactive showed that supplementation with standard vitamin C did not increase plasma concentrations of anti-oxidant at all, whereas antioxidant activity from vitamin C from a squeezed orange lasted about 24 hours. According to research, only about 7% of vitamin C from a cheap supplement even makes it into the blood stream. Liposomal vitamin C (which can cost over 40 pounds a bottle) is a different matter. Natural vitamin E with all 8 tocopherols and tocotrienols can cost over 65 pounds.

The crucial questions then become, ‘How much are you prepared to pay for quality nutritional supplements?’, and, ‘Even at these high prices, are you clear you are not introducing chemicals of concern into your body?’

At least now you know what to look out for!

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